Publications

Larsson E, Fredlund-Fuchs P, Bondjers C, Barkefors I, Heldin J, Gerwins P, Genove G, Arrondel C, Harvey SJ, Kreuger J, Lindahl P. Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1.  Genome Med. 1(11):108, 2009

Ratelade J, Arrondel C, Hamard G, Garbay S, Harvey S, Biebuyck N, Schulz H, Hastie N, Pontoglio M, Gubler MC, Antignac C, Heidet L.. A murine model of Denys-Drash syndrome reveals novel transcriptional targets of WT1 in podocytes. Human Molecular Genetics (in press)

Goldberg S, Harvey SJ, Cunningham J, Tryggvason K, Miner JH. Glomerular filtration is normal in the absence of both agrin and perlecan-heparan sulfate from the glomerular basement membrane. Nephrol Dial Transplant. 24(7):2044-2051, 2009

Harvey SJ, Jarad G, Cunningham J, Goldberg S, Schermer B, Harfe BD, McManus MT, Benzing T, Miner JH. Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease. J Am Soc Nephrol. 19(11):2150-2158, 2008

Harvey SJ, Jarad G, Cunningham J, Rops A, van der Vlag J, Berden JH, Moeller M, Holzman L, Burgess RW, Miner JH. Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity. Am J Pathol 171(1):139-152, 2007

Shannon MB, Patton BL, Harvey SJ, Miner JH. A hypomorphic mutation in the mouse laminin a5 gene (Lama5) causes polycystic kidney disease. J Am Soc Nephrol. 17(7):1913-1922, 2006

Harvey SJ, Perry J, Zheng K, Chen D, Sado Y, Jefferson B, Ninomiya Y, Jacobs R, Hudson BG, Thorner PS. Sequential expression of type IV collagen networks: Testis as a model and relevance to spermatogenesis. Am J Pathol. 168(5):1587-1597, 2006

Zheng K, Perry J, Harvey SJ, Sado Y, Ninomiya Y, Jefferson B, Jacobs R, Hudson BG, Thorner PS. Regulation of collagen type IV genes is organ-specific: Evidence from a canine model of Alport syndrome. Kidney Int. 68(5):2121-2130, 2005 

Gross O*, Beirowski B*, Harvey SJ*, McFadden C, Chen D, Tam S, Thorner PS, Smyth N, Addicks K, Bloch W, Ninomiya Y, Sado Y, Weber M, Vogel WF. DDR1-deficient mice show localized subepithelial GBM thickening with focal loss of slit diaphragms and proteinuria. Kidney Int. 66(1):102-111, 2004  (* equal contribution)

Harvey SJ, Zheng K, Jefferson B, Moak P, Sado Y, Naito I, Ninomiya Y, Jacobs R, Thorner PS. Transfer of the a5(IV) collagen chain gene to smooth muscle restores in vivo expression of the a6(IV) collagen chain in a canine model of Alport syndrome. Am J Pathol. 162(3): 873-885, 2003 

Chen D, Jefferson B, Harvey SJ, Stephens D, Jacobs RM, Thorner PS. Cyclosporine A slows the progressive renal disease of Alport syndrome (X-linked hereditary nephritis): Results from a canine model. J Am Soc Nephrol. 14(3):690-698, 2003 

Harvey SJ, Mount R, Sado Y, Naito I, Ninomiya Y, Harrison R, Jefferson B, Jacobs R, Thorner PS. The inner ear of dogs with X-linked nephritis provides clues to the pathogenesis of hearing loss in X-linked Alport syndrome. Am J Pathol. 159(3):1097-1104, 2001 

Morello R, Zhou G, Dreyer SD, Harvey SJ, Ninomiya Y, Thorner PS, Miner JH, Cole W, Winterpacht A, Zabel B, Oberg KC, Lee B. Regulation of glomerular basement membrane collagen expression by LMX1B contributes to renal disease in nail patella syndrome. Nat Genet. 27(2):205-208, 2001 

Zheng K, Harvey S, Sado Y, Naito I, Ninomiya Y, Jacobs R, Thorner PS. Absence of the a6 chain of collagen type IV in Alport syndrome is related to a failure at the level of protein assembly and does not result in diffuse leiomyomatosis. Am J Pathol. 154(6):1883-1891, 1999 

Harvey SJ, Zheng K, Sado Y, Naito I, Ninomiya Y, Jacobs RM, Hudson BG, Thorner PS. Role of distinct type IV collagen networks in glomerular development and function. Kidney Int. 54(6):1857-1866, 1998 

Saal S, Harvey SJ. MicroRNAs and the kidney: coming of age. Curr Opin Nephrol Hypertens. 18(4):317-323, 2009

Gross O, Borza DB, Anders HJ, Licht C, Weber M, Segerer S, Torra R, Gubler MC, Heidet L, Harvey S, Cosgrove D, Lees G, Kashtan C, Gregory M, Savige J, Ding J, Thorner P, Abrahamson DR, Antignac C, Tryggvason K, Hudson B, Miner JH. Stem cell therapy for Alport syndrome: the hope beyond the hype. Nephrol Dial Transplant. 24(3):731-734, 2009

Harvey SJ, Miner JH. Revisiting the glomerular charge barrier in the molecular era. Curr Opin Nephrol Hypertens 17:393-398, 2008

Harvey SJ, Miner JH. Breaking down the barrier: Evidence against a role for heparan sulfate in glomerular permselectivity. J Am Soc Nephrol. 18(3):672-674, 2007

Harvey SJ and Thorner PS. (2005) Type IV collagen: A network for development, differentiation and disease. In: Advances in Developmental Biology. Extracellular Matrix in Development and Disease, ed. Miner JH. Elsevier, Vol. 15, p. 1-64